Tobacco Documents Online

Sep 1900 TI advises Science Writers about Feinstein, encloses info packet: "Not too long ago we ran into a discourse in "Medical Counterpoint" called "The Intellectual Morbidity of Vital Statistics." It was by Dr. Alvan R. Feinstein. . . and it concerned what he called "egregiously defective statistics" and the erroneous conclusions he said can be drawn from them. The subject so fascinated us that we began our own literature review of the subject. The result, enclosed, may be a good refernce file item for you--or even a take-off point for a feature. . . William Kloepfer, Jr." TIMN 0078608

Sep 1900 TI advises Science Writers about Feinstein research, encloses info packet: "Not too long ago we ran into a discourse in "Medical Counterpoint" called "The Intellectual Morbidity of Vital Statistics." It was by Dr. Alvan R. Feinstein. . . and it concerned what he called "egregiously defective statistics" and the erroneous conclusions he said can be drawn from them. The subject so fascinated us that we began our own literature review of the subject. The result, enclosed, may be a good refernce file item for you--or even a take-off point for a feature. . . William Kloepfer, Jr." TIMN 0078608

17 Jul 1963 Hippo Implications: Discusses TIRC as a "public relations" gesture.

Nov 1965 (est.) "E.J.J." explains the reasons for funding Feinstein--Statute of Limitations in lawsuits.: "Dr. Feinstein's work in this connection is at least in part inspired by Dr. Ian Macdonald's theories of biologic predeterminism in the field of cancer therapy. The importance of this work is in two areas (as well as possibly others), as follows: 1. Should the preliminary indications, that there is no correlation between cigarette smoking and the clinical course of cancer of the lung or larynx, be confirmed, it would be of assistance in disputing the assertions of aggregation and acceleration of cancer by smoking made in certain of the lawsuits. The point is of particular pertinence in respect of the Statute of Limitations. 2. The development of techniques of multi-variable analysis by a man whose training includes both medicine and mathematics should prove valuable in application to the other data, as well as to his own, with regard to questions of causation. E.J.J."

17 Dec 1965 Ad Hoc Cmte Priority: "Projects essentially of "adversary" value.: "The Ad Hoc Committee submitted its "priorities" selected from the recommendations for specific research presented to General Counsel at an earlier meeting. References hereinafter will be as appear from those proposals. The Ad Hoc Committee divided the proposals referred to into three categories: Category A: Projects essentially of "adversary" value. These are considered to have a relatively high priority. Category B: Research having a generally defensive character. Category C. Basic research." Also, Feinstein's $5,600 project is mentioned here.

02 Mar 1966 Feinstein gets $5,600 from CTR: "3/2/66 SP-2 Relationship of cigarette smoking to the clinical course and behavior of cancers of the lung, larynx and rectum, with particular reference to the development of techniques of multivariable analysis. Investigator: Alvan R. Feinstein, M.D. Department of Medicine Yale University School of Medicine Cost: $5,600.00 Duration: One year. Progress: Financial assistance for project described, in the amount of $5,600.00, confirmed (1-7-66) [awaiting instructions as to payments].

25 Sep 1968 TI's Kloepfer Refuses Lloyd Mallan's request to fund a book: TITLE: [TI STATING THEY CAN NOT UNDERWRITE MALLAN L RESEARCH EFFORT IN CONNECTION WITH BOOK SUGGESTED BY LEWIS. (C)]

09 Jun 1970 Alvan Feinstein proposes a "Special Project": "Dear Tom: Enclosed is a copy of a letter dated June 3 that I have received from Dave Hardy concerning a proposed Special Project of Dr. Alvan R. Feinstein. Attached to this copy is a copy of the proposal submitted by Dr. Feinstein. Also enclosed is a copy of my reply to Dave Hardy. Sincerely, H.H.L Ramm, Vice President and General Counsel [RJR]"

16 Jul 1970 SHB had backup funding ready if the Public Health Service turned down Feinstein: "Recently you authorized the expenditure of $31,852 plus minimal overhead to Dr. Alvan R. Feinstein in the event he was unable to secure a grant or financing from the Public Health Service. Dr. Feinstein was most appreciative and has recently advised us that he has been assured that Public Health Service financing will be forthcoming. Thus, unless the Government's perfomance fails to measure up to its promise, the authorized expenditure will not have to be made. Sincerely, David R. Hardy"

19 Apr 1988 SHB recommends Renewal of $484G Feinstein "Special Project": "Dr. Alvan Feinstein has requested a renewal of his CTR Special Project on improved scientific methods in clinical epidemiology. Funding is requested for two years in the amount of $484,960. "Dr. Feinstein plans to broaden his investigation of "epidemiologic necropsy," the method he has developed for using autopsy data in epidemiologic investigations. He believes that this method can provide better estimates of the true occurrence rates of disease." 2015006928

05 Dec 1989 Proposal for Support of Biomedical Research by PM: Murray and Bring report on a Task Force examininig the desirability and feasibiilty of PM's establishing a major program for supporting basic biomedical research. Bates:2023028306 -2023028313 TDO-973967 Bliley Collection-23967 Author: Bring, M.H. (and Murray, R.W.) Recipient: Philip Morris Board of Directors

22 Nov 1993 Luik is advised on how to attack EPA Report: Rothmans' Dr. David Rowland writes Luik about his meet with Bernie O'Neil of Shook Hardy Bacon. O'Neil says the 90% argument is out, because EPA did a one-tailed test. "What has to be attacked is the EPA's assumption that they were justified in using a one-tailed test."